Anxiety /

What medicines treat anxiety?

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Anxiety can be treated using different types of medication depending on the type and severity of anxiety. Chronic anxiety is usually treated with antidepressants, which boost serotonin levels, while short-term anxiety is treated with benzodiazepines, which are fast-acting and leave the system quickly. Buspirone is another medication used for long-term anxiety that affects serotonin levels with fewer side effects than other anxiety medications. Atypical antipsychotics can also be used to treat anxiety, but they may have side effects and can cause tardive dyskinesia, a permanent movement disorder. Some medications, such as anticonvulsants and antihistamines, are used off-label to treat anxiety. It's important to discuss with a doctor which medication is best for individual needs and to be aware of potential side effects and risks associated with their use.


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Many different medications can be used to treat anxiety. Each type of anxiety medication works in a different way, and they often target different symptoms or types of anxiety. Many times, people take multiple anti-anxiety medications together.

There are three main aspects of anxiety that can be treated by medications:

  • Long-term anxiety or “chronic anxiety” is when you feel anxious most days for a significant part of the day. You may feel anxious for no particular reason, or you may have many things that trigger your anxiety each day. To treat chronic anxiety with medication, you usually need to take the same medication every day for several weeks before you feel the full effect.
  • Short-term anxiety or “acute anxiety” is when you experience brief episodes of intense anxiety. These episodes might last a few hours or a few days. The most extreme form of acute anxiety is a panic attack, where you might hyperventilate or feel like your heart is going to explode. Less extreme episodes are usually called anxiety attacks.
  • Insomnia is when you have trouble falling asleep or staying asleep. Many people have trouble falling asleep because they can’t stop worrying at night. But not getting enough sleep can also make you more anxious during the day!

It’s common to experience more than one of these together. For example, you may feel moderately anxious every day, but every once in a while you have an anxiety attack that makes you even more anxious than usual. On a day when you are particularly anxious, you’ll probably also have a harder time falling asleep. Here are a few things to keep in mind when you’re thinking about taking medication for anxiety:

  • Anything that helps with long-term anxiety is likely to also make your anxiety attacks less intense and less frequent.
  • Medications that only help with short-term anxiety tend to cause problems if you take them too often.
  • Treating your anxiety is likely to help you sleep better—and improving your sleep is also likely to help with anxiety!

Antidepressants

Anxiety is not the same thing as depression, but they do often go together. Antidepressants are often effective in treating anxiety as well. They are most commonly used to treat generalized anxiety disorder (GAD) , obsessive-compulsive disorder (OCD) .

Antidepressants are taken daily for long-term anxiety. You usually need to take them every day for several weeks before you feel the full effect.

There are many types of antidepressants. Most of them work by boosting serotonin, a substance in your brain that affects your mood. If one antidepressant doesn’t help you, a different kind might.

Common side effects of antidepressants include:

  • Changes in your sleep, appetite, weight, or sex drive
  • Feeling nauseous or dizzy
  • Headaches

Some of the antidepressants most commonly used to treat anxiety include:

Generic name
Type of antidepressant


Fluoxetine
SSRI
Sertraline
SSRI
Vilazodone
SSRI
Duloxetine
SNRI
Venlafaxine
SNRI
Imipramine
TCA
Bupropion**Atypical

*A few antidepressants, like bupropion, are stimulating and can sometimes increase your anxiety. Many doctors are hesitant to prescribe bupropion to a patient who experiences anxiety. On the other hand, if you have both anxiety and depression, anything that helps with depression will likely also help with anxiety!

For more information, check out our full article on antidepressants.

Buspirone

Buspirone is similar to antidepressants in a few ways: it is taken daily for long-term anxiety, and it works by affecting your serotonin levels. It has relatively few side effects compared to many other anxiety medications.

Benzodiazepines

Benzodiazepines (“benzos”) are fast-acting anti-anxiety medications. They take effect quickly—usually within 30 minutes to an hour. They also leave your system quickly—the strongest effects wear off within a few hours. [6]

Benzodiazepines are generally prescribed to treat short-term anxiety, panic attacks, or insomnia (trouble sleeping). They are also used to treat seizures.

Although benzodiazepines are generally considered safe and effective in the short term, they can become habit-forming in the long term. If you take them too often, after a while you will need more and more to get the same effect [6]. Some people use them as a party drug, and they can become addictive. The way they work in the brain is similar to alcohol—for both better and worse. (One of the reasons alcohol is commonly used in social settings is because it reduces people’s social anxiety—but it can lead to addiction.)

Generic name
Alprazolam
Clonazepam
Diazepam
Lorazepam

Etizolam

For more information, check out our full article on benzodiazepines.

Atypical Antipsychotics

These medications are called “antipsychotics” because they were originally used to treat conditions like schizophrenia and bipolar disorder. More recently, they are being used to treat other conditions, including insomnia (trouble sleeping) and anxiety [7]. The medications used for anxiety are called “atypical” or 2nd-generation antipsychotics.

Like all medications, atypical antipsychotics can have side effects. However, antipsychotics are unique in that they can sometimes cause a movement disorder called tardive dyskinesia, which can become permanent. Be sure to speak with your doctor about warning signs to look out for if you try these medications.

Generic name
Aripiprazole
Quetiapine
Risperidone

For more information, check out our full article on atypical antipsychotics.

Other off-label medications

An off-label medication is something that is typically used to treat one condition, but is sometimes also used to treat something else. For example, anxiety is an off-label use for atypical antipsychotics. Other types of medications that are used off-label to treat anxiety include :

  1. Anticonvulsants, typically used to treat seizures, nerve pain, or fibromyalgia. These are taken daily for long-term anxiety.
  2. Antihistamines, typically used to treat allergies. These can be taken every day for long-term anxiety, or they can be taken as-needed for short-term anxiety.
  3. Beta-blockers, typically used to treat high blood pressure or other heart problems. These are taken as needed for short-term anxiety.

Antihistamines and beta-blockers do not have the same risks as benzodiazepines. Of course, like all medications, there is still the possibility of side effects.


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